Guillainbarre syndrome gbs was first described in 1916 guillain g, 1916 and is approaching its 100th anniversary. Guillain barre syndrome gbs atau yang dikenal dengan acute inflammatory idiopathic polyneuropathy aiip atau yang bisa juga disebut sebagai acute inflammatory demyelinating polyneuropathy aidp adalah suatu penyakit pada susunan saraf yang terjadi secara akut dan menyeluruh, terutama mengenai radiks dan saraf tepi, kadangkadang mengenai saraf otak yang didahului oleh infeksi. Parry mengatakan bahwa, sgb adalah suatu polineuropati yang bersifat ascending dan akut yang sering terjadi setelah 1 sampai 3 minggu setelah infeksi akut. Join researchgate to discover and stay uptodate with the latest research from leading experts in guillainbarre syndrome and many other scientific topics. Scribd is the worlds largest social reading and publishing site. Bab i pendahuluan sindrom guillain barre adalah suatu kelainan sistem saraf akut dan difus yang biasanya timbul setelah suatu infeksi akut atau diakibatkan oleh autoimun, dimana proses imunologis tersebut langsung mengenai radiks spinalis dan saraf perifer, dan juga saraf kranialis. The diagnosis relies heavily on the clinical impression obtained from the history and examination, although cerebro.
The term gbs is often considered to be synonymous with acute inflammatory demyelinating polyradiculoneuropathy aidp, but with the increasing recognition of variants over the past few decades, the number of diseases that fall under the rubric gbs have. Evidencebased information on guillain barre syndrome from hundreds of trustworthy sources for health and social care. Pada beberapa keadaan dapat terjadi setelah vaksinasi atau pembedahan. Guillainbarre syndrome gbs is characterized by rapidly evolving ascending weakness, mild sensory loss and hypo or areflexia, progressing to a nadir over up to four weeks. My case was much worse than the authors, which may account for my disgruntle attitude.
Guillainbarre syndrome is rare guillainbarre syndrome gbs is a rare disorder in which a persons own immune system damages the nerves, causing muscle weakness and sometimes paralysis. Most people recover, but it may take six months to two years or more. Guillain barre syndrome, an overview for the layperson, 9th ed. Hereditary polyneuropathy immunemediated polyneuropathy guillain barre syndrome gbs chronic demyelinating polyneuropathy cidp guillain barr syndrome is an acute inflammatory demyelinating polyneuropathy aidp, a disorder affecting the peripheral nervous system. Guillain barre syndrome hassan bj marabong free download as powerpoint presentation. Guillainbarre syndrome also known as landrys paralysis is an autoimmune disorder in which the peripheral nervous system of a person is attacked by the bodys immune system resulting in rapidonset muscle weakness and degeneration, the disorder can be lifethreatening with the development of weakness in the breathing muscles and requiring mechanical ventilation, dangerous abnormalities in. Guillainbarre syndrome an overview sciencedirect topics. Sindroma guillainbarre dr iskandar japardi fakultas. It can develop over the course of several hours or days, or it may take up to 3 or 4 weeks. Guillain barre syndrome israel pdf ppt case reports.
G uillain barre syndrome gbs is characterized by rapidly progressive symmetric paralysis. Understanding of guillainbarre syndrome gbs has progressed substantially since the seminal 1916 report by guillain et al. Oct 25, 2019 guillain barre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system pns. When you have guillainbarre syndrome, the immune system the bodys natural defences produces harmful antibodies that attack the nerves. Polyradiculoneuropathy, guillain barre strohl syndrome, landry ascending paralysis. Penyebab infeksi terbanyak yang telah diidentifikasi adalah campylobacter jejuni, cytomegalovirus, eipsteinbarr. Etiologi penyebab guillain bare syndrom tidak jelas tidak diketahui. Cbd guillian barre myelin peripheral neuropathy scribd. Once originally considered to be only demyelinating in pathology we now recognise both axonal and demyelinating subtypes. Comprehensive pathophysiology of guillain barre syndrome free download as powerpoint presentation. Pdf guillain barre syndrome gbs is an acute onset, usually monophasic immunemediated disorder of the peripheral nervous system. Neurological disorders free download as powerpoint presentation. Cdc h1n1 flu fact sheet on guillainbarre syndrome gbs. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising.
Panoramageneralparalapersona sinconocimientosmedicos. Guillainbarre syndrome the foundation for peripheral. Classic guillainbarre syndrome gbs is an acute, autoimmune polyradiculopathy characterized by the onset of paresthesias beginning in the finger tips and toes associated with lower extremity weakness that tends to increase in severity and to ascend to affect more proximal muscles and nerves over a period of hours to days. Although guillain, barre, and strohl summarised the syndrome based on observations of two french infantrymen, 2012 saw the beginning of an ambitious collaborative study designed to collect detailed data from at least 1,000 patients worldwide igos. Elsevier advances in neurological therapy guillainbarre syndrome david walk, m. Guillain barre syndrome gbs adalah suatu kelainan sistem kekebalan tubuh. As a result, your muscles have trouble responding to your brain. It is usually triggered by an acute infectious process. A third type of guillain barre syndrome is named acute motorsensory axonal neuropathy amsan. Guillain barre syndrome gbs is a rare immune mediated polyneuropathy that occurs in previously healthy individuals. Sindroma guillain barre guillain barre syndrome gbs chapter pdf available. Dec 14, 2017 a collection of disease information resources and questions answered by our genetic and rare diseases information specialists for guillain barre syndrome. Guillainbarre syndrome is a form of nerve inflammation.
Damage to these nerves makes it hard for them to transmit signals. The purpose of this paper is to provide readers with an understanding of guillain barre and conflictions gbs has with other medical resources and diseases. As a survivor of guillain barre syndrome, i personally did not care for this book. Neurologic problems persist in up to 20 percent of patients with the disease, and onehalf of these patients are severely disabled. Guillainbarre syndrome associated with igg antigd1b antibody. Sebagian besar pasienpasien dengan sindroma guillainbarre sgb ini ditimbulkan oleh adanya infeksi pernapasan atau gastrointestinal 14 minggu sebelum terjadi serangan neurologik. Guillainbarre gheeyan bahray syndrome gbs is a rare inflammatory disorder in which the bodys immune system attacks the protective covering of the peripheral nerves myelin sheath, preventing the nerves from sending signals to the muscles. Patients with amsan have been marked with the worst recovery prognosis because of the rapid severity of. Guillain barre syndrome hassan bj marabong nervous. Our knowledge of the syndrome has hugely expanded since that time. Bab i pendahuluan sindrom guillainbarre sgb atau secara klinis sering disebut poli. Attending this meeting were joel steinberg, a stillrecovering physician, as. Update on guillainbarre syndrome rinaldi 20 journal.
Guillainbarre syndrome gbs is a rapidonset muscle weakness caused by the immune system damaging the peripheral nervous system. The goals of this multicenter controlled trial were. Guillain barre syndrome telah menyelesaikan tugas dalam. Guillain barre syndrome foundation international 2000. Guillainbarre syndrome, gbs, zika virus, zika virus infection outbreak. I realize that everyone is different, and perhaps i should pen my own account. This means that guillain barre syndrome, or a subtype of guillain barre syndrome, affects less than 200,000 people in the us population. Menurut bosch, sgb merupakan suatu sindroma klinis yang ditandai adanya. Unduh sebagai doc, pdf, txt atau baca online dari scribd.
Sindrom guillain barre gbs abstrak sindrom guillainbarre adalah penyakit autoimun yang menimbulkan peradangan dan kerusakan mielin material lemak, terdiri dari lemak dan protein yang membentuk selubung pelindung di sekitar beberapa jenis serat saraf perifer. Guillain barre syndrome case study group free download as word doc. Guillain barre syndrome gbs is an inflammatory disease of the pns and is the most common cause of acute flaccid paralysis, with an annual global incidence of approximately 12 per 100,000. Cpguillain barre syndrome free download as powerpoint presentation. Panoramageneralparalapersona sinconocimientosmedicos publicacionde gbscidp foundationinternational decimaedicion,2010. Guillainbarre syndrome gbs is an acute onset, usually monophasic immunemediated disorder of the peripheral nervous system. The cause is unknown, but most cases seem to be triggered by a bacterial or viral illness. A complete pathophysiology of guillain barre syndrome credits to glaizacute18 and jacqueline lim for the original pathophysiologiesi just placed the necessary diagnostic tests and treatments intended for each complications. The pns nerves connect your brain and spinal cord with the rest of your body. Guillain barre syndrome free download as powerpoint presentation.
The initial symptoms are typically changes in sensation or pain along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body, with both sides being involved. Guillainbarre syndrome health sciences wellness scribd. Guillain barre syndrome is listed as a rare disease by the office of rare diseases ord of the national institutes of health nih. Unduh sebagai docx, pdf, txt atau baca online dari scribd. Guillainbarre syndrome gbs is a rare condition in which a persons immune system attacks the peripheral nerves. Warren, lcdr, mc, usnr, naval hospital jacksonville, jacksonville, florida guillain barre syndrome gbs is a group of autoimmune syndromes consisting of demyelinating and acute axonal degenerating forms of the disease.
Comprehensive pathophysiology of guillainbarre syndrome. Diagnosis and management of guillainbarre syndrome in ten. Guillainbarre syndrome after brachial plexus trauma. Ivig is a treatment made from donated blood that contains healthy antibodies. Guillainbarre syndrome is an autoimmune condition in which the persons. Guillainbarre syndrome associated with the zika virus outbreak in. Aug 29, 2011 guillain barre syndrome is an acute infectious demyelinating polyradiculoneuropathy. Guillainbarre syndrome gbs, sought a means to help others deal with this disorder.
She brought some recovered patients together around her dining room table in suburban philadelphia to start a support organization. Bosch, 1998 sgb mempunyai banyak sinonim, antara lain. Referat gbs gafuran penyakit guillain barre syndrome atau yang biasa disingkat. Sindroma guillain barre sgb merupakan suatu sindroma klinis yang ditandai adanya paralisis flasid yang terjadi secara akut berhubungan dengan proses autoimun dimana targetnya adalah saraf perifer, radiks, dan nervus kranialis. Referat gbs gafuran penyakit guillain barre syndrome atau yang biasa disingkat penyakit gbs adalah gangguan sistem kekebalan tubuh yang menyerang saraf by glavazquez. Newswanger, lcdr, mc, usnr, national naval medical center, bethesda, maryland charles r. Cerebrospinal fluid evaluation demonstrates albuminocytologic dissociation. Unduh sebagai pdf, txt atau baca online dari scribd. Guillainbarre syndrome gbs is a rare, acute, inflammatory demyelinating polyneuropathy with a presentation of progressive ascending motor weakness of the extremities, which may extend to the. Department of neurology, university of chicago at illinois, chicago, illinois walk, d. Ricardo erazo torricelli pediatric neurologist hospital luis calvo mackenna, chile. The most commonly used treatment for guillainbarre syndrome is intravenous immunoglobulin ivig.
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